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| Registros recuperados: 11 | |
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| SILVA,VICTOR D.A.; CUEVAS,CARLOS; MUÑOZ,PATRICIA; VILLA,MONICA; AHUMADA-CASTRO,ULISES; HUENCHUGUALA,SANDRO; SANTOS,CLEONICE C. DOS; ARAUJO,FILLIPE M. DE; FERREIRA,RAFAEL S; SILVA,VANESSA B. DA; SILVA,JULIANA H.C. E; SOARES,ÉRICA N.; VELOZO,EUDES S.; SEGURA-AGUILAR,JUAN; COSTA,SILVIA L.. |
| ABSTRACT Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be responsible for neurotoxic damage observed in animals. We investigated the involvement of programmed cell death (PCD) and autophagy on the mechanism of cell death induced by a total extract (TAE) of alkaloids and fraction (F32) from P. juliflora leaves composed majoritary of juliprosopine in a model of neuron/glial cell co-culture. We saw that TAE (30 µg/mL) and F32 (7.5 µg/mL) induced reduction in ATP levels and changes in mitochondrial membrane potential at 12 h exposure. Moreover, TAE and F32 induced caspase-9 activation, nuclear condensation and neuronal death at 16 h exposure. After 4 h,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Programmed cell death; Autophagy; Glial cells; Neurons; Piperidine alkaloids; Prosopis juliflora.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100247 |
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| Nagy, F; Cazalets, J; Moulins, M. |
| In decapod Crustacea, the rhythmic activity of the pyloric filter is programmed within a network of 14 neurons in the stomatogastric nervous system. The pyloric network activity is underlied by both the endogenous regenerative properties of its neurons and the organization of their synaptic connections. Both factors are controlled by central modulatory neurons. Two of these neurons were identified, the APM neuron, which induces, and the PS neuron, which suppresses, the regenerative properties of pyloric neurons. APM can start and PS can stop the rhythmic pyloric activity, but both of them can also change its expression. Because of this control, the pyloric network can produce several types of motor pattern. |
| Tipo: Text |
Palavras-chave: Crustacea; Alimentary organs; Neurons; Neurophysiology. |
| Ano: 1987 |
URL: http://archimer.ifremer.fr/doc/1987/acte-1386.pdf |
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| Castejón,Orlando J.; Dailey,Michael E.. |
| The localization of GluR1 subunits of ionotropic glutamate receptors in the glial cells and inhibitory neurons of cerebellar cortex and their association with the climbing and parallel fibers, and basket cell axons were studied. Samples of P14 and P21 rat cerebellar cortex were exposed to a specific antibody against GluR1 subunit(s) of AMPA receptors and were examined with confocal laser scanning microscopy. GluR1 strong immunoreactivity was confined to Purkinje cell and the molecular layer. Weak GluR1 immunoreactivity was observed surrounding some Golgi cells in the granule cell layer. Intense GluR1 immunoreactivity was localized around Purkinje, basket, and stellate cells. Purkinje cells expressed strong GluR1 immunoreactivity surrounding the cell body,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Glutamate receptors; Glia; Neurons; Confocal microscopy. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452009000200001 |
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| Diniz,C.G.; Magalhães,N.G.M.; Sousa,A.A.; Santos Filho,C.; Diniz,D.G.; Lima,C.M.; Oliveira,M.A.; Paulo,D.C.; Pereira,P.D.C.; Sherry,D.F.; Picanço-Diniz,C.W.. |
| The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia are long- and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and mid-arctic tundra of Canada and Alaska and winters on the north and east coasts of South America. A. macularia breeds in a broad distribution across most of North America from the treeline to the southern United States. It winters in the southern United States, and Central and South America. The autumn migration route of C. pusilla includes a non-stop flight over the Atlantic Ocean, whereas autumn route of A. macularia is largely over land. Because of this difference in their migratory paths and the visuo-spatial recognition tasks involved, we hypothesized that hippocampal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hippocampus; Neurons; Microglia; Shorebirds; Stereology; Morphometry. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100603 |
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| Navarrete Gómez,Patricia; Ormeño,David; Miranda,Antonio; Sánchez Gutiérrez,Raúl; Romero Mejía,Fernando; Parodi Rivera,Jorge. |
| Since the 1970s, There have been studies of the venom of Latrodectus sp. spiders, in particular the latrotoxin (LTX) of Latrodectus mactans. Many of the studies were aimed at understanding the action of the venom on the muscular system. Now accepted that LTX is able to generate a calcium-permeable membrane pore and modulate the release of synaptic vesicles that activate a receptor and induce cellular changes. Interestingly, when work began with venom obtained from the Latrodectus sp present in Chile, it generated clinical indications similar to the bite of this spider in another country, with some differences in intensity. The purpose of the first studies was to understand the systemic mechanisms of this venom, and other active compounds were studied for... |
| Tipo: Journal article |
Palavras-chave: Latrodectus venom; Oocytes; Neurons; Spermatozoa; Contraceptive. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300012 |
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| HIDALGO,CECILIA; BULL,RICARDO; MARENGO,JUAN J; PÉREZ,CLAUDIO F; DONOSO,PAULINA. |
| The effects of redox reagents on the activity of the intracellular calcium release channels (ryanodine receptors) of skeletal and cardiac muscle, or brain cortex neurons, was examined. In lipid bilayer experiments, oxidizing agents (2,2'-dithiodipyridine or thimerosal) modified the calcium dependence of all single channels studied. After controlled oxidation channels became active at sub µM calcium concentrations and were not inhibited by increasing the calcium concentration to 0.5 mM. Subsequent reduction reversed these effects. Channels purified from amphibian skeletal muscle exhibited the same behavior, indicating that the SH groups responsible for modifying the calcium dependence belong to the channel protein. Parallel experiments that... |
| Tipo: Journal article |
Palavras-chave: Calcium dependence; Neurons; Redox state; Ryanodine receptors; Sarcoplasmic reticulum; Skeletal and cardiac muscle. |
| Ano: 2000 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200011 |
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| Registros recuperados: 11 | |
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